VOCABULARY
Protein sorting
Proteins are carried in vesicles from the endoplasmic reticulum to the Golgi apparatus, where they are further processed and sorted for transport to lysosomes, the plasma membrane, or cell secretion.
KDEL
This is a receptor of an integral membrane protein that is found in the Golgi/intermediate compartment and is responsible for retrieving ER proteins with a C-terminal KDEL sequence that have escaped. This occurs in all COPI-coated transport carriers that carry retrograde traffic.
Melanosomes
Organelles that generate and store melanin, a common biological pigment with a unique set of features such as a high refractive index, semiconducting properties, and high fossilization potential.
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