Friday, March 25, 2022

VOCAB JOURNAL #10

 JOURNAL #10 -VOCABULARY



ACTIN TREADMILLING 


    Constant removal of actin monomers from filament pointed ends and their reincorporation at barbed ends are required for the cell mobility. 


FORMINS


    Formins are a collection of proteins involved in actin polymerization and associated with actin filaments' fast-growing end (barbed end).


Cofilin


    Cofilin is an actin-binding protein that controls filament depolymerization and dynamics.



Saturday, March 19, 2022

VOCAB JOURNAL #9

 VOCABULARY 




Protein sorting

Proteins are carried in vesicles from the endoplasmic reticulum to the Golgi apparatus, where they are further processed and sorted for transport to lysosomes, the plasma membrane, or cell secretion.


KDEL

This is a receptor of an integral membrane protein that is found in the Golgi/intermediate compartment and is responsible for retrieving ER proteins with a C-terminal KDEL sequence that have escaped. This occurs in all COPI-coated transport carriers that carry retrograde traffic.


Melanosomes

 Organelles that generate and store melanin, a common biological pigment with a unique set of features such as a high refractive index, semiconducting properties, and high fossilization potential.

Friday, March 4, 2022

Reflection Journal #8

 Hello Journal,



    A few days ago in my Cell Biology class, we were discussing the prions. A prion is a protein that causes normal proteins in the brain to fold improperly.  "Mad Cow disease" was one of the disorders caused by prions that we discussed in class. Mad cow disease is a disease that infects cattle and causes a gradual deterioration of the brain and spinal cord. And variant Creutzfeldt-Jakob disease (vCJD) is a deadly degenerative disease that affects the brain and spinal cord in humans over time. Bovine spongiform encephalopathy is another name for this condition (or BSE). I smiled at the name "Mad Cow disease" when I first heard it since it seemed amusing to me. However, it is so awful that it can be fatal. This is a brain disease that can be passed from mature cattle to humans through infected meat. Humans can contract the sickness by eating tainted meat. When it comes from cattle, the sickness is called Creutzfeldt-Jakob disease, and it causes dementia and death. This is a rather uncommon condition. The illness is marked by rapid mental decline, which can happen in as little as a few months. The vast majority of victims suffer due to their injuries and fall into a coma. Because research is still ongoing, there is presently no treatment for this condition. However, according to certain countries that have implemented a prohibition on giving meat and bone meals to cattle in areas where the disease has been detected, the disease itself has reduced.







Journal #14

 Vocabulary  SCNT - Somatic cell nuclear transfer The nucleus of a somatic (body) cell is transferred to the cytoplasm of an enucleated egg ...